9-(2-叠氮基-2-脱氧-alpha-D-阿拉伯呋喃糖基)-9H-嘌呤-6-胺合成路线 (共 3 条)
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
0.166667 h; Ambient temperature;
参考文献
Fukukawa; Uedao; Hirano
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1582 - 1592
反应条件
1: 79 percent / triethylamine, DMAP / CH2Cl2 / 0.5 h / Ambient temperature
2: 92 percent / LiN3 / hexamethylphosphoric acid triamide / 4 h / Ambient temperature
3: 87 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.17 h / Ambient temperature
View Scheme
参考文献
Fukukawa; Uedao; Hirano
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1582 - 1592
反应条件
1: 92 percent / LiN3 / hexamethylphosphoric acid triamide / 4 h / Ambient temperature
2: 87 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.17 h / Ambient temperature
View Scheme
参考文献
Fukukawa; Uedao; Hirano
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1582 - 1592