反应条件
1: para-iodoanisole With n-butyllithium; zinc dibromide in tetrahydrofuran; hexane
T=-78 - 20°C;
2: 2-iodo-2-cyclopent-2-en-1-one With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; trifuran-2-yl-phosphane in N,N-dimethyl-formamide
T=20°C; Negishi coupling; 5 h; Title compound not separated from byproducts;
参考文献
Pour, Milan; Spulak, Marcel; Balsanek, Vojtech; Kunes, Jiri; Kubanova, Petra; Buchta, Vladimir
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 13 p. 2843 - 2866