3-(N,N-二甲基氨基甲酰)苯甲酸甲酯合成路线 （共 5 条）
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in tetrahydrofuran; methanol
T=20°C; 2 h;
参考文献
KYOWA HAKKO KOGYO CO., LTD.
Patent: EP1700856 A1, 2006 ;
Location in patent: Page/Page column 135 ;
EP 1700856 A1
反应条件
4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane
T=20°C; 21 h;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1466898 A1, 2004 ;
Location in patent: Page 71 ;
反应条件
thionyl chloride in 1,4-dioxane
参考文献
Allen and Hansburys Limited
Patent: US5021429 A1, 1991 ;
US 5021429 A
参考文献
Parik, Patrik; Kulhanek, Jiri; Ludwig, Miroslav; Wagner, Roman; Rotrekl, Ivan; Drahonovsky, Dusan; Meca, Ludek; Smidkova, Marketa; Tobrman, Tomas; Dvorak, Dalimil
Organometallics, 2010 , vol. 29, # 18 p. 4135 - 4138
反应条件
(i) SOCl2, (ii) /BRN= 605257/, dioxane, H2O; Multistep reaction;
参考文献
Allen u. ? Ltd.
Patent: DE2821410 , 1978 ;
Chem.Abstr., 1979 , vol. 90, # 121258
