1,2,3,6-四氢吡啶合成路线 （共 66 条）
反应条件
in chloroform
1.5 h; Heating;
参考文献
Muller, Jean-Claude; Ramuz, Henri; Wagner, Hans-Peter
Helvetica Chimica Acta, 1983 , vol. 66, # 3 p. 809 - 813
反应条件
1: 18 h / 110 °C
3: 22 percent / NEt3 / dimethylformamide / 18 h / Ambient temperature
View Scheme
参考文献
Muller; Ramuz
Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1445 - 1453
反应条件
1: ethanol; H2O / Heating
2: 26 percent / benzene / 11 h / Irradiation
View Scheme
参考文献
Coyle, John D.; Newport, Graham L.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 93 - 96
反应条件
1: 66 percent / sodium hydroxide / H2O / 0.25 h
2: 1.) silver trifluoroacetate, 2.) NaHCO3 / 1.) ether, -15 deg C, 15 min, room temperature, 2.) methanol, water, room temperature
3: 60 percent / triphenyltin hydride / toluene / 3.3 h / 120 °C
View Scheme
参考文献
Clive, Derrick L. J.; Chittattu, Gim J.; Farina, Vittorio; Kiel, William A.; Menchen, Steven M.; et al.
Journal of the American Chemical Society, 1980 , vol. 102, # 13 p. 4438 - 4447
反应条件
1: 76 percent / benzene / Heating
2: HCl / methanol / 72 h / Heating
View Scheme
参考文献
Kaafarani, M.; Crozet, M. P.; Surzur, J. M.
Bulletin de la Societe Chimique de France, 1989 , # 1 p. 114 - 118
反应条件
1: 95 percent / aq. Na2CO3 / dioxane / 3 h / 20 °C
2: 64 percent / m-chloroperbenzoic acid / CH2Cl2 / 7 h / 20 °C
View Scheme
参考文献
D'Andrea; Michalson; Freeman; Chidester; Szmuszkovicz
Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 3133 - 3137
反应条件
1: sodium hydroxide / water / 0 - 20 °C
2: glycerol / dimethyl sulfoxide / 48 h / 4 °C / pH 7.2 / aq. phosphate buffer; Enzymatic reaction
View Scheme
参考文献
Robin, Aelig; Koehler, Valentin; Jones, Alison; Ali, Afruja; Kelly, Paul P.; O'Reilly, Elaine; Turner, Nicholas J.; Flitsch, Sabine L.
Beilstein Journal of Organic Chemistry, 2011 , vol. 7, art. no. 7, p. 1494 - 1498
反应条件
mesohemin in N,N-dimethyl-formamide
Ambient temperature;
参考文献
Guillemin, Jean-Claude; Denis, Jean-Marc; Lasne, Marie-Claire; Ripoll, Jean-Louis
Tetrahedron, 1988 , vol. 44, # 14 p. 4447 - 4456
反应条件
1: 18 h / 110 °C
3: 94 percent / 28percent aq. NaOH / CH2Cl2; H2O / 1 h / 0 °C / pH=7.5 - 8.5
4: 86 percent / 3percent aq. NaOH / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Muller; Ramuz
Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1445 - 1453
反应条件
in o-xylene
T=120°C; 0.5 h;
参考文献
Muller; Ramuz
Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1445 - 1453
