四氢-2H-吡喃-2-醇合成路线 （共 136 条）
反应条件
1: 85 percent / hydrogen chloride / benzene / 3 h / Ambient temperature
2: 85 percent / 3N aq. natrium hydroxide / 0.5 h / Heating
3: 1.) LDA / 1.) THF, -78 deg C, 1 h, 2.) THF, -78 deg C then RT
4: KOtBu / tetrahydrofuran / 1 h / Ambient temperature
View Scheme
参考文献
Ley, Steven V.; Lygo, Barry; Organ, Helen M.; Wonnacott, Anne
Tetrahedron, 1985 , vol. 41, # 18 p. 3825 - 3836
反应条件
1: 93 percent
2: 98 percent / H2 / 10percent Pd-C
3: PCC, 4 Angstroem molecular sieves
View Scheme
参考文献
Ihara, Masataka; Taniguchi, Takahiko; Yamada, Masami; Tokunaga, Yuji; Fukumoto, Keiichiro
Tetrahedron Letters, 1995 , vol. 36, # 44 p. 8071 - 8074
反应条件
1: potassium carbonate
2: Raney nickel; cyclohexane / Hydrogenation
View Scheme
参考文献
Gaumeton; Glacet
Bulletin de la Societe Chimique de France, 1959 , p. 1501,1504
反应条件
Re2O7 in dichloromethane
T=20°C; 0.0833333 h; Inert atmosphere;
参考文献
Sittiwong, Wantanee; Richardson, Michael W.; Schiaffo, Charles E.; Fisher, Thomas J.; Dussault, Patrick H.
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 1526 - 1532
反应条件
1: potassium carbonate
2: Raney nickel; ethanolic KOH / Hydrogenation
View Scheme
参考文献
Glacet; Blanchard-Bielli
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1958 , vol. 247, p. 1467,1468, 1469
反应条件
Re2O7 in dichloromethane
T=20°C; 1 h;
参考文献
Sittiwong, Wantanee; Richardson, Michael W.; Schiaffo, Charles E.; Fisher, Thomas J.; Dussault, Patrick H.
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 1526 - 1532
反应条件
palladium diacetate; tributylphosphine; diethylzinc in hexane; toluene
T=20°C; 18 h;
参考文献
Kimura, Masanari; Shimizu, Masamichi; Tanaka, Shuji; Tamaru, Yoshinao
Tetrahedron, 2005 , vol. 61, # 15 p. 3709 - 3718
反应条件
tin in tetrahydrofuran; water
Ambient temperatureIrradiation;
参考文献
Einhorn, Cathy; Luche, Jean-Louis
Journal of Organometallic Chemistry, 1987 , vol. 322, p. 177 - 184
参考文献
Christlbauer, Monika; Schieberle, Peter
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 24 p. 13122 - 13130
反应条件
1: potassium carbonate / zuletzt bei 90grad/500 Torr
2: Raney nickel; ethanolic KOH-solution / Hydrogenation
View Scheme
参考文献
Glacet
Bulletin de la Societe Chimique de France, 1953 , p. 1056,1058
