四氢-2H-吡喃-2-醇合成路线 （共 136 条）
反应条件
(i) DMF, (ii) aq. KOH, (iii) /BRN= 102415/, Et2O; Multistep reaction;
参考文献
Bergel'son,L.D. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1963 , p. 454 - 456
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1963 , p. 506 - 509
反应条件
hydrogen bromide; sodium methylate; triphenylphosphine in methanol; water
参考文献
BASF Aktiengesellschaft
Patent: US5395993 A1, 1995 ;
反应条件
Re2O7 in dichloromethane T=20°C; 2 h; Inert atmosphere;
参考文献
Sittiwong, Wantanee; Richardson, Michael W.; Schiaffo, Charles E.; Fisher, Thomas J.; Dussault, Patrick H.
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 1526 - 1532
反应条件
silver(l) oxide das Salz der 5-Hydroxy-valeriansaeure entsteht;
参考文献
Gaudry; Berlinguet
Canadian Journal of Research, Section B: Chemical Sciences, 1949 , vol. 27, p. 287
反应条件
1: KMnO4; natrium carbonate / Hydrogenation.das Salz der 5-Hydroxy-valeriansaeure entsteht 2: concentrated H2SO4; HBr 3: red phosphorus; bromine / 120 °C View Scheme
参考文献
Gaudry; Berlinguet
Canadian Journal of Research, Section B: Chemical Sciences, 1949 , vol. 27, p. 287
参考文献
Singh, Pankajkumar R.; Surpur, Mandar P.; Patil, Sachin B.
Tetrahedron Letters, 2008 , vol. 49, # 20 p. 3335 - 3340
反应条件
1: 93 percent 2: 98 percent / H2 / 10percent Pd-C 3: PCC, 4 Angstroem molecular sieves View Scheme
参考文献
Ihara, Masataka; Taniguchi, Takahiko; Yamada, Masami; Tokunaga, Yuji; Fukumoto, Keiichiro
Tetrahedron Letters, 1995 , vol. 36, # 44 p. 8071 - 8074
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=20°C; Mitsunobu reaction; 2 h;
参考文献
Azzouz, Rabah; Bischoff, Laurent; Fouquet, Marc-Henri; Marsais, Francis
Synlett, 2005 , # 18 art. no. D17805ST, p. 2808 - 2810
反应条件
2: aq. HCl / aq. ethanol View Scheme
参考文献
Glacet,C.; Couturier,J.-C.
Bulletin de la Societe Chimique de France, 1962 , p. 2097 - 2102
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=20°C; Mitsunobu reaction; 2 h;
参考文献
Azzouz, Rabah; Bischoff, Laurent; Fouquet, Marc-Henri; Marsais, Francis
Synlett, 2005 , # 18 art. no. D17805ST, p. 2808 - 2810
