1-甲基-1,2,3,6-四氢吡啶合成路线 （共 25 条）
反应条件
formic acid; potassium formiate
T=150°C;
参考文献
Lukes
Collection of Czechoslovak Chemical Communications, 1947 , vol. 12, p. 71,74
反应条件
hydrogen bromide
16 h; Heating; Yield given;
参考文献
Bailey, Judith M.; Booth, Harold; Al-Shirayda, Hatif A.R.Y.; Trimble, Mary L.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , p. 737 - 744
参考文献
Lukes et al.
Collection of Czechoslovak Chemical Communications, 1954 , vol. 19, p. 949,951
参考文献
Lukes; Pliml
Collection of Czechoslovak Chemical Communications, 1956 , vol. 21, p. 1602,1605
参考文献
Ferles
Collection of Czechoslovak Chemical Communications, 1958 , vol. 23, p. 479,480
参考文献
Lukes et al.
Collection of Czechoslovak Chemical Communications, 1954 , vol. 19, p. 949,951
参考文献
Lukes
Collection of Czechoslovak Chemical Communications, 1947 , vol. 12, p. 71,74
反应条件
1: 30percent hydrogen peroxide / ethanol / 60 °C
2: CH2Cl2 / 1.) 0 deg C, 1 h, 2.) room temperature, 15 min
3: KCN, sodium acetate, pH 4.0 / CH2Cl2; H2O / 0.25 h
4: 50 percent / potassium tert-butoxide / tetrahydrofuran / 0.08 h / Ambient temperature
View Scheme
参考文献
Grierson,D.S.; Harris,M.; Husson,H.P.
Journal of the American Chemical Society, 1980 , vol. 102, p. 1064
反应条件
trifluorormethanesulfonic acid
T=25°C; 4 h;
参考文献
Klumpp, Douglas A.; Beauchamp, Philip S.; Sanchez Jr., Gregorio V.; Aguirre, Sharon; De Leon, Sarah
Tetrahedron Letters, 2001 , vol. 42, # 34 p. 5821 - 5823
反应条件
1: potassium t-butoxide / dimethylsulfoxide
2: 82 percent / diethyl ether / 25 °C
View Scheme
参考文献
Warren; Knaus
Journal of Heterocyclic Chemistry, 1982 , vol. 19, # 5 p. 1259 - 1260
