1-甲基-1,2,3,6-四氢吡啶合成路线 （共 25 条）
反应条件
1: potassium t-butoxide / dimethylsulfoxide
2: 71 percent / diethyl ether / 25 °C
View Scheme
参考文献
Warren; Knaus
Journal of Heterocyclic Chemistry, 1982 , vol. 19, # 5 p. 1259 - 1260
反应条件
hydrogen; RhH(CO)(triphenylphosphine)3 in benzene
T=100°C; P=60004.8 Torr; 6 h;
参考文献
Prokai-Tatrai, K.; Toeroes, S.; Heil, B.
Journal of Organometallic Chemistry, 1986 , vol. 315, p. 231 - 236
反应条件
potassium tert-butylate in dimethyl sulfoxide
T=91.6°C; 48 h; sealed tube;
参考文献
Cook, A. Gilbert; Schering, Christine A.; Campbell, Pauline A.; Hayes, Samantha S.
Tetrahedron Letters, 2005 , vol. 46, # 33 p. 5451 - 5454
反应条件
lt;Rh((+)-BINAP)(COD)gt;+ in tetrahydrofuran
T=60°C; 20 h;
参考文献
Cook, A. Gilbert; Schering, Christine A.; Campbell, Pauline A.; Hayes, Samantha S.
Tetrahedron Letters, 2005 , vol. 46, # 33 p. 5451 - 5454
反应条件
potassium carbonate in toluene
T=110°C; 4.5 h; Heating / reflux;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2005/66176 A1, 2005 ;
Location in patent: Page/Page column 80-81 ;
WO 2005/066176 A1
