1: 2-Bromo-N,N-dimethylaniline With magnesium in tetrahydrofuran Heating; 2: 1-bromo-2-chloro-benzene in tetrahydrofuran T=60°C; 2.25 h; 3: chlorodi-tert-butylphosphine With copper(l) chloride in tetrahydrofuran T=60°C; 20 h; Further stages.;
参考文献
Kaye, Steven; Fox, Joseph M.; Hicks, Frederick A.; Buchwald, Stephen L.
Advanced Synthesis and Catalysis, 2001 , vol. 343, # 8 p. 789 - 794
trans-[(2-tolyl)3P]2PdCl2 in xylene byproducts: o-Cl-C6H4-CH2CN; mixt. of degassed educts heated at 120°C, until the color of mixt. turning to black (24 h); evapn., chromy. (silica gel), reduced pressure distn.;
