1: 1-bromo-2-chloro-benzene With iodine; magnesium in tetrahydrofuran
T=20°C; 1 h;
2: 2-chloro-benzaldehyde in tetrahydrofuran
T=20°C; 1 h;
参考文献
Chu, Ling; Wang, Xiao-Chen; Moore, Curtis E.; Rheingold, Arnold L.; Yu, Jin-Quan
Journal of the American Chemical Society, 2013 , vol. 135, # 44 p. 16344 - 16347
Antelo Miguez, Jose M.; Adrio, Luis Angel; Sousa-Pedrares, Antonio; Vila, Jose M.; Hii, King Kuok
Journal of Organic Chemistry, 2007 , vol. 72, # 20 p. 7771 - 7774
1: 88 percent / PdCl2(CH3CN)2; 2'-(dicyclohexyl-phosphanyl)-2,4,6-triisopropyl-biphenyl; CS2CO3 / acetonitrile / 12 h / 90 °C
2: 83 percent / Pd2dba3; di-t-butyl-(2',4',6'-triisopropyl-biphenyl-2-yl)-phosphane; KOH / dioxane; H2O / 8 h / 100 °C
View Scheme
参考文献
Anderson, Kevin W.; Ikawa, Takashi; Tundel, Rachel E.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2006 , vol. 128, # 33 p. 10694 - 10695
1: 9-Bromophenanthrene With magnesium in tetrahydrofuran
T=60°C;
2: 1-bromo-2-chloro-benzene in tetrahydrofuran
T=60°C; 2.33333 h;
3: chloro-dicyclohexylphosphine With copper(l) chloride in tetrahydrofuran
T=20°C; 48 h; Further stages.;
参考文献
Yin, Jingjun; Rainka, Matthew P.; Zhang, Xiao-Xiang; Buchwald, Stephen L.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1162 - 1163
1: 100 percent / K3PO4 / Pd(OAc)2 / dimethylformamide; H2O / 3 h / 20 °C
2: (2',6'-dimethoxybiphenyl-2-yl)dicyclohexylphosphine / Pd3(OAc)6 / tetrahydrofuran; H2O / 21 h / 60 °C
View Scheme
参考文献
Antelo Miguez, Jose M.; Adrio, Luis Angel; Sousa-Pedrares, Antonio; Vila, Jose M.; Hii, King Kuok
Journal of Organic Chemistry, 2007 , vol. 72, # 20 p. 7771 - 7774
