DL-2-氨基-4-(4-甲基苯基)-4-氧代丁酸盐酸盐合成路线 （共 3 条）
反应条件
hydrogenchloride; water in 1,4-dioxane
8 h; Reflux;
参考文献
Kumar, Sunil; Gawandi, Vijay B.; Capito, Nicholas; Phillips, Robert S.
Biochemistry, 2010 , vol. 49, # 36 p. 7913 - 7919
反应条件
1.1: copper(ll) bromide / chloroform; ethyl acetate / 5 h / Reflux
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 3 h / 0 °C / Inert atmosphere
2.2: 20 °C / Inert atmosphere
3.1: hydrogenchloride; water / 1,4-dioxane / 8 h / Reflux
View Scheme
参考文献
Kumar, Sunil; Gawandi, Vijay B.; Capito, Nicholas; Phillips, Robert S.
Biochemistry, 2010 , vol. 49, # 36 p. 7913 - 7919
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 3 h / 0 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: hydrogenchloride; water / 1,4-dioxane / 8 h / Reflux
View Scheme
参考文献
Kumar, Sunil; Gawandi, Vijay B.; Capito, Nicholas; Phillips, Robert S.
Biochemistry, 2010 , vol. 49, # 36 p. 7913 - 7919
