n-(4-甲基吡啶-3-基)氨基甲酸甲酯合成路线 (共 2 条)
反应条件
potassium tert-butylate in tetrahydrofuran
T=30°C;
参考文献
BIOCRYST PHARMACEUTICALS, INC.; BABU, Yarlagadda S.; KOTIAN, Pravin L.; KUMAR, V. Satish; WU, Minwan; LIN, Tsu-Hsing
Patent: WO2011/31554 A2, 2011 ;
Location in patent: Page/Page column 194 ;
WO 2011/031554 A1
反应条件
pyridine in dichloromethane
T=20°C; 48 h; Cooling with ice;
参考文献
Gehringer, Matthias; Pfaffenrot, Ellen; Bauer, Silke; Laufer, Stefan A.
ChemMedChem, 2014 , vol. 9, # 2 p. 277 - 281