1.1: NaOMe / methanol / 1 h / 20 °C 1.2: 59 percent / p-TsOH*H2O / dimethylformamide / 3 h / 50 °C 2.1: 41 percent / TsOH*H2O / dimethylformamide / 4 h / 20 °C 3.1: 100 percent / pyridine; DMAP / 16 h / 20 °C 4.1: 88 percent / NaN3 / dimethylformamide / 14 h / 120 °C 5.1: 76 percent / H2 / Raney nickel / ethanol / 3 h / 20 °C / atmospheric pressure 6.1: 90 percent / aq. HCl / 3 h / 80 °C View Scheme