1-氧代-1,2-二氢异喹啉-3-羧酸甲酯合成路线 （共 6 条）
反应条件
1: trichlorophosphate; N-ethyl-N,N-diisopropylamine / toluene / 5 h / |Reflux 2: sodium hydroxide / ethanol / 0.5 h / |Reflux View Scheme
参考文献
Yuan, Yunyun; Elbegdorj, Orgil; Beletskaya, Irina O.; Selley, Dana E.; Zhang, Yan
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 18 p. 5045 - 5048
反应条件
trichlorophosphate in methanol T=130°C; 0.166667 h; Microwave irradiation;
参考文献
Saari, Raimo; Toermae, Jonna-Carita; Nevalainen, Tapio
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 2 p. 939 - 950
反应条件
1: 82 percent / POBr3; K2CO3 / acetonitrile / 1.5 h / Heating
2: 90 percent / K2PO4 / Pd(PPh3)4 / dimethylformamide / 5 h / 80 °C
3: 95 percent / NaOH / aq. ethanol / 1 h / Heating
View Scheme
参考文献
Janin, Yves L.; Roulland, Emmanuel; Beurdeley-Thomas, Arnaud; Decaudin, Didier; Monneret, Claude; Poupon, Marie-France
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 4 p. 529 - 532
反应条件
lithium hydroxide hydrate in 1,4-dioxane
T=20°C; 1 h;
参考文献
Dou, Dengfeng; Viwanathan, Prasanth; Li, Yi; He, Guijia; Alliston, Kevin R.; Lushington, Gerald H.; Brown-Clay, Joshua D.; Padmanabhan; Groutas, William C.
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 6 p. 836 - 843
反应条件
1: trichlorophosphate; N-ethyl-N,N-diisopropylamine / toluene / 5 h / |Reflux
2: bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 0.5 h / 130 °C
View Scheme
参考文献
Yuan, Yunyun; Elbegdorj, Orgil; Beletskaya, Irina O.; Selley, Dana E.; Zhang, Yan
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 18 p. 5045 - 5048
反应条件
potassium carbonate; phosphorus oxytribromide in acetonitrile
Heating;
参考文献
Stevenson, Louise; Pimlott, Sally L.; Sutherland, Andrew
Tetrahedron Letters, 2007 , vol. 48, # 40 p. 7137 - 7139
