4-(苄氧基)-3-溴苯甲醛合成路线 (共 9 条)
反应条件
tetra-(n-butyl)ammonium iodide; potassium carbonate in N,N-dimethyl-formamide T=20°C; 2.5 h;
参考文献
TAISHO PHARMACEUTICAL CO., LTD
Patent: EP1845095 A1, 2007 ;
Location in patent: Page/Page column 36-37 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=90°C; 3 h;
参考文献
Bhattarai, Bharat Raj; Kafle, Bhooshan; Hwang, Ji-Sun; Khadka, Deegendra; Lee, Sun-Myung; Kang, Jae-Seung; Ham, Seung Wook; Han, Inn-Oc; Park, Hwangseo; Cho, Hyeongjin
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 21 p. 6161 - 6165
反应条件
1: 4-hydroxy-benzaldehyde With bromine in methanol; chloroform T=20°C; 22 h; 2: benzyl chloride With potassium carbonate in N,N-dimethyl-formamide 1.25 h; Inert atmosphereReflux;
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 35 p. 7120 - 7133
反应条件
1: Br2 / CHCl3 / 2 h / 40 °C 2: K2CO3 / dimethylformamide / 70 °C View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 14 p. 1102 - 1104
反应条件
copper; potassium carbonate; 4-hydroxy-benzaldehyde T=180 - 200°C;
参考文献
Kametani,T.; Fukumoto,K.
Journal of the Chemical Society, 1964 , p. 6141 - 6146
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform T=20°C; 4 h;
参考文献
Potter, Barry Victor Lloyd; Woo, Lok Wai Lawrence; Purohit, Atul; Reed, Michael John; Sutcliffe, Oliver Brook; Bubert, Christian
Patent: US2004/19016 A1, 2004 ;
Location in patent: Page/Page column 39 ;
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 72 h / 40 °C 2: sodium methylate / ethanol / 1 h / 20 °C 3: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / toluene; water / 2 h / Reflux 4: triethylamine / toluene; acetonitrile / 18 h / Reflux 5: hydrogen / palladium 10 on activated carbon / ethyl acetate; ethanol / 4 h / 50 °C / 3040.2 Torr View Scheme
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio
Patent: WO2012/15704 A2, 2012 ;
WO 2012/015704 A2
反应条件
dicobalt octacarbonyl; potassium carbonate; methyloxirane in methanol T=60°C; P=760 Torr; 10 h;
参考文献
Boyarskii; Zhesko; Lanina
Russian Journal of Applied Chemistry, 2005 , vol. 78, # 11 p. 1844 - 1848