1-羟基环戊烷-1-羧酸甲酯合成路线 （共 8 条）
反应条件
sulfuric acid
Ambient temperature;
参考文献
Roussis, Vassilios; Gloer, Katherine B.; Wiemer, David F.
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2011 - 2015
反应条件
1: 75 percent / potassium cyanide / H2O / 1 h / Ambient temperature
2: 49 percent / concentrated hydrochloric acid / 2.5 h / Heating
3: 92 percent / H2SO4 / Ambient temperature
View Scheme
参考文献
Roussis, Vassilios; Gloer, Katherine B.; Wiemer, David F.
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2011 - 2015
反应条件
1: 92 percent / sodium metabisulfite
2: 75 percent / potassium cyanide / H2O / 1 h / Ambient temperature
3: 49 percent / concentrated hydrochloric acid / 2.5 h / Heating
4: 92 percent / H2SO4 / Ambient temperature
View Scheme
参考文献
Roussis, Vassilios; Gloer, Katherine B.; Wiemer, David F.
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2011 - 2015
反应条件
1: 49 percent / concentrated hydrochloric acid / 2.5 h / Heating
2: 92 percent / H2SO4 / Ambient temperature
View Scheme
参考文献
Roussis, Vassilios; Gloer, Katherine B.; Wiemer, David F.
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2011 - 2015
反应条件
Behandeln mit Schwefelsaeure oder mit waessr. Oxalsaeure-Loesung;
参考文献
Meerwein
Justus Liebigs Annalen der Chemie, 1919 , vol. 419, p. 165
反应条件
magnesium
1.) THF,; 2.) THF, r.t., 12 h -> reflux, 6.5 h; Yield given. Multistep reaction;
参考文献
Pettit, George R.; Thomas, Evan G.
Canadian Journal of Chemistry, 1982 , vol. 60, p. 629 - 633
反应条件
1: Behandeln des Reaktionsgemischs mit konz. Schwefelsaeure oder mit waessriger Oxalsaeure-Loesung
2: bei der Oxydation
View Scheme
参考文献
Meerwein
Justus Liebigs Annalen der Chemie, 1919 , vol. 419, p. 165
参考文献
Meerwein; Unkel
Justus Liebigs Annalen der Chemie, 1910 , vol. 376, p. 157
