反应条件
1: SO3*pyridine, triethylamine / dimethylsulfoxide / 0.5 h / 23 °C 2: 1) NaH / 1) THF, 23 deg C, 30 min, 2) THF, 23 deg C, 40 min 3: 81 mg / NaBH4 / methanol / 0.67 h / -25 °C 4: 65percent aq. acetic acid / tetrahydrofuran / 2 h / 50 °C 5: 90 percent / imidazole / dimethylformamide / 1 h / 23 °C 6: 95 percent / H2 / napthalene*Cr(CO)3 / tetrahydrofuran / 23 h / 45 °C / 55163.1 Torr 7: 100 percent / tetrabutylammonium fluoride (TBAF) / tetrahydrofuran / 13 h / 23 °C 8: 100 percent / 10percent aq. NaOH / methanol / 13 h / 0 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 2 p. 309 - 322
