5-甲基-2-(3-硝基苯基)-1H-苯并咪唑合成路线 （共 3 条）
反应条件
hydrogenchloride; dihydrogen peroxide in acetonitrile
T=20°C; 0.833333 h;
参考文献
Bahrami, Kiumars; Khodaei, Mohammad Mehdi; Kavianinia, Iman
Synthesis, 2007 , # 4 p. 547 - 550
反应条件
toluene-4-sulfonic acid in para-xylene
T=140°C; 18 h; Inert atmosphere;
参考文献
Keurulainen, Leena; Salin, Olli; Siiskonen, Antti; Kern, Jan Marco; Alvesalo, Joni; Kiuru, Paula; Maass, Matthias; Yli-Kauhaluoma, Jari; Vuorela, Pia
Journal of Medicinal Chemistry, 2010 , vol. 53, # 21 p. 7664 - 7674
反应条件
1: pyridine; 4-(N,N-dimethlyamino)pyridine / 0.25 h / 60 °C / Microwave irradiation; Inert atmosphere
2: toluene-4-sulfonic acid / para-xylene / 18 h / 140 °C / Inert atmosphere
View Scheme
参考文献
Keurulainen, Leena; Salin, Olli; Siiskonen, Antti; Kern, Jan Marco; Alvesalo, Joni; Kiuru, Paula; Maass, Matthias; Yli-Kauhaluoma, Jari; Vuorela, Pia
Journal of Medicinal Chemistry, 2010 , vol. 53, # 21 p. 7664 - 7674
