2,6,6-三甲基-6,7-二氢-1H-吲哚-4(5h)-酮合成路线 （共 3 条）
反应条件
ammonium acetate; acetic acid
T=90°C; Paal-Knorr Pyrrole Synthesis; 4 h; Irradiation;
参考文献
Gonzalez-Chavez, Rodolfo; Martinez, Roberto; Torre-Bouscoulet, Maria Eugenia; Gallo, Marco; Gonzalez-Chavez, Marco Martin
Chemical and Pharmaceutical Bulletin, 2014 , vol. 62, # 1 p. 16 - 24
反应条件
1-methyl-pyrrolidin-2-one; tetrakis(triphenylphosphine) palladium(0); lt;3THF*Mg2Cl2O*TiNCOgt;
T=100°C; 12 h;
参考文献
Mori, Miwako; Uozumi, Yasuhiro; Shibasaki, Masakatsu
Heterocycles, 1992 , vol. 33, # 2 p. 819 - 830
反应条件
1.1: potassium hydroxide / water; ethanol / 0.25 h
1.2: 12 h / 20 °C
2.1: acetic acid; ammonium acetate / 3 h / 140 °C
View Scheme
参考文献
CHONG KUN DANG PHARMACEUTICAL CORP.; KIM, Yuntae; LEE, Changsik; YANG, Hyun-mo; CHOI, Hojin; MIN, Jaeki; KIM, Soyoung; KIM, Dal-Hyun; HA, Nina; KIM, Jung-Min; LIM, Hyojin; KO, Eunhee
Patent: WO2013/62344 A1, 2013 ;
