二氢-1-甲基-2,4(1H,3H)-嘧啶二酮合成路线 （共 8 条）
反应条件
phosphoric acid dibutyl ester in toluene
T=110°C; 5 h;
参考文献
Agrawal, Sumit K.; Sathe, Manisha; Kaushik, M. P.; Halve, A. K.
Tetrahedron Letters, 2012 , vol. 53, # 45 p. 5996 - 5999,4
Title/Abstract Show Details
Agrawal, Sumit K.; Sathe, Manisha; Halve; Kaushik
Tetrahedron Letters, 2012 , vol. 53, # 45 p. 5996 - 5999
反应条件
hydrogenchloride in water
2 h; Heating / reflux;
参考文献
QUEEN'S UNIVERSITY AT KINGSTON
Patent: WO2004/9559 A2, 2004 ;
Location in patent: Page 33 ;
反应条件
ethanol; platinum
Hydrogenation;
参考文献
Hilbert
Journal of the American Chemical Society, 1932 , vol. 54, p. 2076,2081
反应条件
1.1: trifluoroacetic acid / dichloromethane / 2 h / 0 °C
1.2: 2 h / 0 - 10 °C
2.1: phosphoric acid dibutyl ester / toluene / 5 h / 110 °C
View Scheme
参考文献
Agrawal, Sumit K.; Sathe, Manisha; Kaushik, M. P.; Halve, A. K.
Tetrahedron Letters, 2012 , vol. 53, # 45 p. 5996 - 5999,4
Title/Abstract Show Details
Agrawal, Sumit K.; Sathe, Manisha; Halve; Kaushik
Tetrahedron Letters, 2012 , vol. 53, # 45 p. 5996 - 5999
反应条件
hydrogenchloride; potassium cyanate
参考文献
Gearien; Binkley
Journal of Organic Chemistry, 1958 , vol. 23, p. 491
反应条件
hydrogenchloride; cyanic acid sodium salt
参考文献
Brown et al.
Journal of the Chemical Society, 1955 , p. 211,216
反应条件
hydrogenchloride
T=45.1 - 60.2°C; Kinetics;
参考文献
Blagoeva,I.B. et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1979 , p. 1115 - 1122
反应条件
bromine; acetic acid
参考文献
Brown et al.
Journal of the Chemical Society, 1955 , p. 211,216
Full Text Show Details
Gearien; Binkley
Journal of Organic Chemistry, 1958 , vol. 23, p. 491
