2-甲基-4(5)硝基咪唑合成路线 （共 56 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide Reflux;
参考文献
Varshney, Vandana; Mishra, Nripendra N.; Shukla, Praveen K.; Sahu, Devi P.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 2 p. 661 - 666
参考文献
Skupin, Rolf; Cooper, Trevor G.; Froehlich, Roland; Prigge, Joerg; Haufe, Guenter
Tetrahedron Asymmetry, 1997 , vol. 8, # 14 p. 2453 - 2464
反应条件
phosphoric acid; acetic anhydride in water T=25 - 30°C; 2.5 h; Yield given;
参考文献
Kraft, M. Ya.; Kochergin, P. M.; Tsyganova, A. M.; Shlikhunova, V. S.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 10 p. 861 - 863
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 10 p. 1246 - 1248
反应条件
nitric acid; acetic anhydride in acetic acid T=40 - 45°C; 1.03333 h;
参考文献
Suwinski, Jerzy; Salwinska, Ewa
Polish Journal of Chemistry, 1987 , vol. 61, # 7-12 p. 913 - 920
反应条件
sulfuric acid; nitric acid
参考文献
Grimmett, M. Ross; Hua, Sio-Tiok; Chang, Kuei-Choo; Foley, Sandra A.; Simpson, Jim
Australian Journal of Chemistry, 1989 , vol. 42, # 8 p. 1281 - 1289
反应条件
sodium hydroxide; sodium peroxodisulphate; potassium hexacyanoferrate(III) in dichloromethane; water 0.166667 h;
参考文献
Adebayo, Adelaide T. O. M.; Bowman, W. Russell; Salt, W. G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 2819 - 2828
反应条件
sulfuric acid in acetic acid T=140°C; 5 h; Yields of byproduct given;
参考文献
Rao, A. K. S. Bhujanga; Rao, C. Gundu; Singh, B. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 17 p. 2399 - 2402
反应条件
pyridine in dimethyl sulfoxide T=135 - 140°C; 10 h; or with various acids or bases in different solvents; Product distribution;
参考文献
Rao, A. K. S. Bhujanga; Rao, C. Gundu; Singh, B. B.
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3702 - 3704
反应条件
sulfuric acid in acetic acid T=140°C; 5 h; Yields of byproduct given;
参考文献
Rao, A. K. S. Bhujanga; Rao, C. Gundu; Singh, B. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 17 p. 2399 - 2402
反应条件
acetic acid in N,N-dimethyl-formamide T=130 - 140°C; 5 h; Yields of byproduct given;
参考文献
Rao, A. K. S. Bhujanga; Rao, C. Gundu; Singh, B. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 17 p. 2399 - 2402
