2,5-二甲氧基四氢呋喃合成路线 （共 286 条）
反应条件
iron(III) chloride heptahydrate in water
T=60°C; Paal-Knorr pyrrole synthesis;
参考文献
Azizi, Najmedin; Khajeh-Amiri, Alireza; Ghafuri, Hossein; Bolourtchian, Mohammad; Saidi, Mohammad Reza
Synlett, 2009 , # 14 p. 2245 - 2248
反应条件
sodium tetrahydroborate; sulfuric acid; water in tetrahydrofuran; methanol
T=10 - 20°C; 1.5 h; Yields of byproduct given;
参考文献
Verardo, Giancarlo; Dolce, Anna; Toniutti, Nicoletta
Synthesis, 1999 , # 1 p. 74 - 79
反应条件
potassium acetate; acetic acid in water
Heating;
参考文献
El Gendy, A. M.; Mallouli, A.; Lepage, Y.
Synthesis, 1980 , # 11 p. 898 - 899
反应条件
potassium acetate; acetic acid in water
Heating;
参考文献
El Gendy, A. M.; Mallouli, A.; Lepage, Y.
Synthesis, 1980 , # 11 p. 898 - 899
反应条件
ionic liquid immobilized on γ-Fe2O3(at)SiO2 nanoparticles in water
T=100°C; Clauson-Kaas Synthesis; 1.16667 h;
参考文献
Ma, Fei-Ping; Li, Pei-He; Li, Bao-Le; Mo, Li-Ping; Liu, Ning; Kang, Hui-Jun; Liu, Ya-Nan; Zhang, Zhan-Hui
Applied Catalysis A: General, 2013 , vol. 457, p. 34 - 41
反应条件
in acetic acid
3 h; Heating;
参考文献
Martinez, Gregory R.; Grieco, Paul A.; Srinivasan, Chidambaram V.
Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3760 - 3761
反应条件
acetic acid
2 h; Heating / reflux;
参考文献
CEPHALON, INC.; CEPHALON FRANCE
Patent: EP1586559 A1, 2005 ;
Location in patent: Page/Page column 64 ;
反应条件
1: 2,5-dimethoxy-tetrahydrofuran With hydrogenchloride in water
T=0°C;
2: acetone-1,3-dicarboxylic acid; 4-fluorobenzenemethanamine hydrochloride With sodium acetate in water
T=20 - 50°C; 3.5 h;
3: With sodium hydroxide in water
T=0°C; pH=10;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2004/9588 A1, 2004 ;
Location in patent: Page 48 ;
WO 2004/009588 A1
反应条件
sodium tetrahydroborate; sulfuric acid in tetrahydrofuran; methanol
T=10 - 35°C; 14 h;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1541576 A1, 2005 ;
Location in patent: Page/Page column 68 ;
EP 1541576 A1
反应条件
in acetic acid
T=120°C; 2 h;
参考文献
Jefford, Charles W.; Sienkiewicz, Krzysztof; Thornton, Steven R.
Tetrahedron Letters, 1994 , vol. 35, # 34 p. 6271 - 6274
