2,5-二甲氧基四氢呋喃合成路线 （共 286 条）
反应条件
in water
T=150°C; Paal-Knorr condensation; 0.5 h; Microwave irradiation;
参考文献
Rivera, Sonya; Bandyopadhyay, Debasish; Banik, Bimal K.
Tetrahedron Letters, 2009 , vol. 50, # 39 p. 5445 - 5448
反应条件
montmorillonite K-10
T=100°C; 0.0833333 h; microwave irradiation;
参考文献
Abid, Mohammed; Landge, Shainaz M.; Toeroek, Bela
Organic Preparations and Procedures International, 2006 , vol. 38, # 5 p. 495 - 500
反应条件
1: 58 percent / CaCl2 / CH2Cl2 / 24 h / Ambient temperature
2: 1.) Mg, ZnBr2, / 1.) THF, RT; 30 min, 2.) THF, RT;
View Scheme
参考文献
Brown, Dearg S.; Bruno, Maurizio; Davenport, Raymond J.; Ley, Steven V.
Tetrahedron, 1989 , vol. 45, # 13 p. 4293 - 4308
参考文献
Rault, Isabelle; Foloppe, Marie-Paule; Rault, Sylvain; Robba, Max
Heterocycles, 1993 , vol. 36, # 9 p. 2059 - 2066
反应条件
1: 2,5-dimethoxy-tetrahydrofuran With water
2 h; Reflux;
2: α-amino propionitrile hydrochloride With sodium acetate in dichloromethane
T=20°C;
参考文献
Kucukdisli, Murat; Opatz, Till
Journal of Organic Chemistry, 2013 , vol. 78, # 13 p. 6670 - 6676
反应条件
ionic liquid immobilized on γ-Fe2O3(at)SiO2 nanoparticles in water
T=100°C; Clauson-Kaas Synthesis; 1.5 h;
参考文献
Ma, Fei-Ping; Li, Pei-He; Li, Bao-Le; Mo, Li-Ping; Liu, Ning; Kang, Hui-Jun; Liu, Ya-Nan; Zhang, Zhan-Hui
Applied Catalysis A: General, 2013 , vol. 457, p. 34 - 41
反应条件
acetic acid in water; 1,2-dichloro-ethane
T=80°C; Paal-Knorr reaction;
参考文献
Hulcoop, David G.; Lautens, Mark
Organic Letters, 2007 , vol. 9, # 9 p. 1761 - 1764
反应条件
1: in 1,4-dioxane
72 h; Heating;
2: With hydrogenchloride in 1,4-dioxane
Heating; Further stages.;
参考文献
Dey, Sanjeev K.; Lightner, David A.
Journal of Organic Chemistry, 2007 , vol. 72, # 24 p. 9395 - 9397
反应条件
sodium tetrahydroborate; sulfuric acid; water in tetrahydrofuran; methanol
T=10 - 20°C; 1.5 h; Yield given;
参考文献
Verardo, Giancarlo; Dolce, Anna; Toniutti, Nicoletta
Synthesis, 1999 , # 1 p. 74 - 79
参考文献
Liu, Wei; Ma, Yuan; Yin, Yingwu; Zhao, Yufen
Bulletin of the Chemical Society of Japan, 2006 , vol. 79, # 4 p. 577 - 579
