2,5-二甲氧基嘧啶-4-胺合成路线 （共 2 条）
反应条件
1: in toluene T=27 - 87°C; 2: in water; toluene T=40°C; 3: With hydroxylamine in water; toluene T=68 - 81°C; pH=4.44 - 7.40; pH-valueSolventTemperatureTimeReagent/catalyst;
参考文献
Dow AgroSciences LLC; Bland, Douglas C.; Hamilton, Christopher T.
Patent: US2014/81024 A1, 2014 ;
Location in patent: Paragraph 0027 ;
反应条件
1: ethyl acetate / 13.5 h / 78 °C 2: hydroxylamine hydrochloride; sodium hydroxide / ethyl acetate; water 3: ethyl acetate; water / 20 - 50 °C View Scheme
参考文献
DOW AGROSCIENCES LLC
Patent: US2011/295003 A1, 2011 ;
