L-3-(2-萘)-丙氨酸合成路线 （共 21 条）
反应条件
hydrogenchloride
2 h; Heating;
参考文献
Rodriguez; Bernad; Galas; Lignon; Laur; Aumelas; Martinez
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 3 p. 245 - 253
反应条件
1: 80 percent / 1 M NaOH / aq. ethanol / 6 h / Ambient temperature
2: 97 percent / 0.17 h / 160 °C
3: 88 percent
4: 92 percent / 6 N aq. HCl / 2 h / Heating
View Scheme
参考文献
Rodriguez; Bernad; Galas; Lignon; Laur; Aumelas; Martinez
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 3 p. 245 - 253
反应条件
1: 92 percent / EtONa / ethanol / 6 h / Heating
2: 80 percent / 1 M NaOH / aq. ethanol / 6 h / Ambient temperature
3: 97 percent / 0.17 h / 160 °C
4: 88 percent
5: 92 percent / 6 N aq. HCl / 2 h / Heating
View Scheme
参考文献
Rodriguez; Bernad; Galas; Lignon; Laur; Aumelas; Martinez
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 3 p. 245 - 253
反应条件
1: 88 percent
2: 92 percent / 6 N aq. HCl / 2 h / Heating
View Scheme
参考文献
Rodriguez; Bernad; Galas; Lignon; Laur; Aumelas; Martinez
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 3 p. 245 - 253
反应条件
cobalt(II) chloride
T=30°C; pH=8; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Vaidya, Bhalchandra K.; Kuwar, Suyog S.; Golegaonkar, Sandeep B.; Nene, Sanjay N.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 74, # 3-4 p. 184 - 191
反应条件
cobalt(II) chloride
T=30°C; pH=8; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Vaidya, Bhalchandra K.; Kuwar, Suyog S.; Golegaonkar, Sandeep B.; Nene, Sanjay N.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 74, # 3-4 p. 184 - 191
反应条件
water; chymotrypsin
T=25°C; Rate constant;
参考文献
Gerisch; Jakubke; Kreuzfeld
Tetrahedron Asymmetry, 1995 , vol. 6, # 12 p. 3039 - 3045
参考文献
Calmes, Monique; Daunis, Jacques; Mai, Nathalie
Tetrahedron Asymmetry, 1997 , vol. 8, # 10 p. 1641 - 1648
反应条件
Yield given. Multistep reaction;
参考文献
Belokon', Yu. N.; Chernoglazova, N. I.; Ivanova, E. V.; Popkov, A. N.; Saporovskaya, M. B.; et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1988 , vol. 37, # 12 p. 2541 - 2544
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1988 , # 12 p. 2818 - 2821
反应条件
sodium hydroxide in water
参考文献
Egusa, Syun; Takagi, Jun; Sisido, Masahiko; Imanishi, Yukio
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 7 p. 2195 - 2202
