(S)-N-Boc-吡咯烷-2-甲醛 N-(叔丁氧羰基)-L-脯氨醛合成路线 (共 52 条)
参考文献
Wright, Dennis L.; Weekly, R. Matt; Groff, Royce; McMills, Mark C.
Tetrahedron Letters, 1996 , vol. 37, # 13 p. 2165 - 2168
反应条件
1: 61 percent / 0.4 M cerium chloride / methanol / 67 h / 40 - 45 °C
2: 10percent HCl / methanol / 1 h / Ambient temperature
3: diethyl phosphorocyanidate, triethylamine / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 40 min
5: 80 percent / H2 / 5percent Pd-C / ethanol / 1 h / Ambient temperature
View Scheme
参考文献
Mori, Shigehiro; Aoyama, Toyohiko; Shioiri, Takayuki
Tetrahedron Letters, 1986 , vol. 27, # 50 p. 6111 - 6114