(S)-5,6,7,8-四氢-5-氧代咪唑并[1,5-c]嘧啶-7-甲酸甲酯合成路线 （共 9 条）
反应条件
1: 95 percent / acetonitrile / 6 h / Heating 2: 85 percent / diisopropylethylamine / 120 h / Heating 3: acetonitrile / 24 h / Heating 4: Zn, acetic acid / methanol / 7 h / Ambient temperature 5: aq. HCl / 1.5 h / Heating View Scheme
参考文献
Chivikas, Cleo J.; Hodges, John C.
Journal of Organic Chemistry, 1987 , vol. 52, # 16 p. 3591 - 3594
反应条件
in N,N-dimethyl-formamide
T=70°C; 6 h;
参考文献
Alberto, Roger; Pak, Jae Kyoung
Patent: US2007/77195 A1, 2007 ;
Location in patent: Page/Page column 8; 9 ;
反应条件
sodium azide; diphenyl-phosphinic acid in acetonitrile
T=-41 - 20°C;
参考文献
Garcia-Egido, Eduardo; Fernandez-Suarez, Miryam; Munoz, Luis
Journal of Organic Chemistry, 2008 , vol. 73, # 7 p. 2909 - 2911
参考文献
Guillen, Frederic; Bregeon, Delphine; Plaquevent, Jean-Christophe
Tetrahedron Letters, 2006 , vol. 47, # 8 p. 1245 - 1248
反应条件
in N,N-dimethyl-formamide
T=60°C; 12 h;
参考文献
Shitama, Hiroaki; Katsuki, Tsutomu
Chemistry - A European Journal, 2007 , vol. 13, # 17 p. 4849 - 4858
反应条件
1: 100 percent / AcCl / 24 h
2: 67 percent / dimethylformamide / 12 h / 60 °C
View Scheme
参考文献
Shitama, Hiroaki; Katsuki, Tsutomu
Chemistry - A European Journal, 2007 , vol. 13, # 17 p. 4849 - 4858
反应条件
in N,N-dimethyl-formamide
T=60°C; 8 h;
参考文献
Nayak, Surendra Kumar; Monga, Vikramdeep; Kaur, Navneet; Jain, Rahul
Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 6 p. 1265 - 1269
反应条件
in dichloromethane
0.25 h; Heating; Yield given;
参考文献
Chivikas, Cleo J.; Hodges, John C.
Journal of Organic Chemistry, 1987 , vol. 52, # 16 p. 3591 - 3594
参考文献
Schloegl; Woidich
Monatshefte fuer Chemie, 1956 , vol. 87, p. 679,690
