4-(对羟基苯基)-2-丁醇合成路线 （共 9 条）
反应条件
phosphate buffer; Rhodococcus ruber DSM 44541 cells; acetone T=30°C; pH=7.5; 44 h;
参考文献
Kosjek, Birgit; Stampfer, Wolfgang; Van Deursen, Ruud; Faber, Kurt; Kroutil, Wolfgang
Tetrahedron, 2003 , vol. 59, # 48 p. 9517 - 9521
反应条件
1: With formic acid; palladium 10 on activated carbon; ammonium formate in methanol T=50°C; 15 h; 2: With sodium hypochlorite; 4-acetylamino 2,2,6,6-tetramethylpiperidin-N-oxyl; sodium hydrogencarbonate; potassium bromide in dichloromethane; water T=0 - 20°C; 3 h;
参考文献
Wu, Haotian; Hintermann, Lukas
Synthesis (Germany), 2013 , vol. 45, # 7 art. no. SS-2013-Z0022-PSP, p. 888 - 892
反应条件
acetone
(-)-1-<4-methoxy-phenyl>-butanol-(3);
参考文献
Sosa
Annales de Chimie (Cachan, France), 1940 , vol. <11> 14, p. 5,54
Full Text Show Details
Kin
Yakugaku Zasshi, 1942 , vol. 62, p. 455; 456; dtsch. Ref. S. 132, 133
Chem.Abstr., 1951 , p. 4222
Full Text Show Details
Kin
Yakugaku Zasshi, 1943 , vol. 63, p. 103,104
Chem.Abstr., 1951 , p. 4222
反应条件
(-)-1-<4-methoxy-phenyl>-butanol-(3);
参考文献
Lederer; Polonsky
Trav. Soc. Chim. biol., 1942 , vol. 24, p. 1386,1390
反应条件
alcohol dehydrogenase from Thermoanaerobium brockii; NADH-specific (R)-selective-ADH; YcnD-oxidoreductase
T=30°C; pH=7.5; 24 h; aq. bufferResolution of racemateEnzymatic reaction; optical yield given as percent eeenantiospecific reaction;
参考文献
Voss, Constance V.; Gruber, Christian C.; Faber, Kurt; Knaus, Tanja; Macheroux, Peter; Kroutil, Wolfgang
Journal of the American Chemical Society, 2008 , vol. 130, # 42 p. 13969 - 13972
反应条件
lipase B from Candida antarctica in tetrahydrofuran; hexane
T=35°C; P=0.1 Torr; 0.166667 h; Molecular sieveEnzymatic reaction;
参考文献
Kitayama, Takashi; Isomori, Sachiko; Nakamura, Kaoru
Tetrahedron Asymmetry, 2013 , vol. 24, # 11 p. 621 - 627
反应条件
lipase of Pseudomonas fluorescens (Amano PS) in tetrahydrofuran; hexane
T=35°C; P=0.1 Torr; 12 h; Molecular sieveEnzymatic reaction; enantioselective reaction;
参考文献
Kitayama, Takashi; Isomori, Sachiko; Nakamura, Kaoru
Tetrahedron Asymmetry, 2013 , vol. 24, # 11 p. 621 - 627
反应条件
lipase from Alcaligenessp. in tetrahydrofuran; di-isopropyl ether
T=35°C; P=0.1 Torr; 1 h; Molecular sieveEnzymatic reaction; TimeReagent/catalyst; enantioselective reaction;
参考文献
Kitayama, Takashi; Isomori, Sachiko; Nakamura, Kaoru
Tetrahedron Asymmetry, 2013 , vol. 24, # 11 p. 621 - 627
反应条件
phosphate buffer; Rhodococcus ruber DSM 44541 cells; acetone
T=30°C; pH=7.5; 44 h;
参考文献
Kosjek, Birgit; Stampfer, Wolfgang; Van Deursen, Ruud; Faber, Kurt; Kroutil, Wolfgang
Tetrahedron, 2003 , vol. 59, # 48 p. 9517 - 9521
