(R)-3-(甲氧基甲基)吗啉盐酸盐合成路线 （共 3 条）
反应条件
palladium on carbon in methanol
T=20°C; 24 h; Inert atmosphere;
参考文献
MEDIVIR AB; AYESA, Susana; BELDA, Oscar; BJÖRKLUND, Catarina; NILSSON, Magnus; RUSSO, Francesco; SAHLBERG, Christer; WIKTELIUS, Daniel
Patent: WO2013/95275 A1, 2013 ;
Location in patent: Page/Page column 48 ;
反应条件
1.1: silver(l) oxide / tetrahydrofuran / 0.5 h / 20 °C
1.2: 48 h / 45 °C
2.1: palladium on carbon / methanol / 24 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
MEDIVIR AB; AYESA, Susana; BELDA, Oscar; BJÖRKLUND, Catarina; NILSSON, Magnus; RUSSO, Francesco; SAHLBERG, Christer; WIKTELIUS, Daniel
Patent: WO2013/95275 A1, 2013 ;
反应条件
1.1: triethylamine / N,N-dimethyl-formamide / 3 h / 20 °C
2.1: silver(l) oxide / tetrahydrofuran / 0.5 h / 20 °C
2.2: 48 h / 45 °C
3.1: palladium on carbon / methanol / 24 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
MEDIVIR AB; AYESA, Susana; BELDA, Oscar; BJÖRKLUND, Catarina; NILSSON, Magnus; RUSSO, Francesco; SAHLBERG, Christer; WIKTELIUS, Daniel
Patent: WO2013/95275 A1, 2013 ;
