6-氟-苯并二氢吡喃-4-酮海因合成路线 （共 27 条）
反应条件
hydrogenchloride 1.) CH2Cl2, RT, 20 min, 2.) steam bath, 1.5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 47, # 21 p. 4081 - 4085
反应条件
sodium hypochlorite T=0°C; Further byproducts given. Title compound not separated from byproducts;
参考文献
Lipinski; Bordner; Butterfield; Marinovic
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1793 - 1799
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 11 p. 1716 - 1720
参考文献
Mizuguchi; Achiwa; Wakamatsu; Terao
Tetrahedron Asymmetry, 1994 , vol. 5, # 8 p. 1407 - 1410
反应条件
hydrogenchloride; sodium hypochlorite
T=25°C;
参考文献
Lipinski; Bordner; Butterfield; Marinovic
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1793 - 1799
反应条件
sodium hypochlorite
T=0°C; Further byproducts given. Title compound not separated from byproducts;
参考文献
Lipinski; Bordner; Butterfield; Marinovic
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1793 - 1799
参考文献
Pfizer Inc.
Patent: US4431828 A1, 1984 ;
