1: hexadecanoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine in ethyl acetate T=20°C; 1 h; 2: 4-hydroxy-3-methoxy-benzylamine in ethyl acetate T=20°C; 12 h;

1: 3-methoxy-4-hydroxybenzylamine hydrochloride With sodium hydrogencarbonate in water T=20°C; 0.5 h; 2: n-hexadecanoyl chloride in chloroform; water T=20°C; 0.5 h;

borate buffer; N-ethyl-N,N-diisopropylamine in water T=37°C; 48 h; pH = 9.0, chicken liver acetone powder (Sigma Chem. Co.);

1: 17.2 percent / diisopropylethylamine, borate buffer / H2O / 48 h / 37 °C / pH = 9.0, chicken liver acetone powder (Sigma Chem. Co.) 2: 12.9 percent / diisopropylethylamine, borate buffer / H2O / 48 h / 37 °C / pH = 9.0, chicken liver acetone powder (Sigma Chem. Co.) View Scheme

1: 17.2 percent / diisopropylethylamine, borate buffer / H2O / 48 h / 37 °C / pH = 9.0, chicken liver acetone powder (Sigma Chem. Co.) 2: 12.9 percent / diisopropylethylamine, borate buffer / H2O / 48 h / 37 °C / pH = 9.0, chicken liver acetone powder (Sigma Chem. Co.) View Scheme

diethyl ether

1: palladium; aqueous alcoholic hydrochloric acid / Hydrogenation 2: natrium carbonate View Scheme

sodium carbonate