2-氯-4-三氟甲氧基苯胺合成路线 （共 2 条）
参考文献
SANOFI-AVENTIS DEUTSCHLAND GMBH
Patent: US2007/197539 A1, 2007 ;
US 20070197539 A1
反应条件
1: 2-chloro-4-trifluoromethoxyaniline With hydrogenchloride in water
T=0°C;
2: With sodium nitrite in water
0.666667 h;
3: sodium cyanide in water
T=0 - 20°C;
参考文献
ONO Pharmaceutical Co., Ltd.
Patent: EP2154139 A1, 2010 ;
Location in patent: Page/Page column 29 ;
EP 2154139 A1
