6-氯-1,3-二甲基脲嘧啶合成路线 （共 66 条）
反应条件
1: H2O
2: NaNO2, acetic acid / H2O
View Scheme
参考文献
Pfleiderer; Schuendehuette
Justus Liebigs Annalen der Chemie, 1958 , vol. 612, p. 158,162
反应条件
sodium hydrogencarbonate in ethanol
3 h; Heating;
参考文献
Reis, Lucinda V.; Lobo, Ana M.; Prabhakar, Sundaresan; Duarte, Mariana P.
European Journal of Organic Chemistry, 2003 , # 1 p. 190 - 208
反应条件
1: 80 percent / NaHCO3 / ethanol / 3 h / Heating
2: 95 percent / iPr2NEt / tetrahydrofuran / 2 h / 0 - 20 °C
3: 36 percent / toluene / 1 h
View Scheme
参考文献
Reis, Lucinda V.; Lobo, Ana M.; Prabhakar, Sundaresan; Duarte, Mariana P.
European Journal of Organic Chemistry, 2003 , # 1 p. 190 - 208
参考文献
Bischoff, Kerstin; Girreser, Ulrich; Heber, Dieter; Schuett, Martin
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2006 , vol. 61, # 4 p. 486 - 494
参考文献
Bischoff, Kerstin; Girreser, Ulrich; Heber, Dieter; Schuett, Martin
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2006 , vol. 61, # 4 p. 486 - 494
反应条件
in N,N-dimethyl-formamide
18 h; Reflux;
参考文献
Wu, Yuen-Jen; Liao, Chen-Chieh; Jen, Cheng-Hung; Shih, Yu-Chiao; Chien, Tun-Cheng
Chemical Communications, 2010 , vol. 46, # 26 p. 4821 - 4823
反应条件
T=130°C; 0.05 h; microwave irradiation;
参考文献
Fang, Woei-Ping; Cheng, Yuh-Tsyr; Cheng, Yann-Ru; Cherng, Yie-Jia
Tetrahedron, 2005 , vol. 61, # 12 p. 3107 - 3113
反应条件
sodium hydrogencarbonate in ethanol
3 h; Heating;
参考文献
Reis, Lucinda V.; Lobo, Ana M.; Prabhakar, Sundaresan; Duarte, Mariana P.
European Journal of Organic Chemistry, 2003 , # 1 p. 190 - 208
反应条件
in neat (no solvent)
T=180°C; 3 h;
参考文献
Nishigaki, Sadao; Sato, Junko; Shimizu, Kayoko; Furukawa, Kiyoko; Senga, Keitaro; Yoneda, Fumio
Chemical & Pharmaceutical Bulletin, 1980 , vol. 28, # 1 p. 142 - 149
反应条件
1: 56 percent
2: 12 percent / CuCl2, PdCl2, O2 / dimethylformamide; H2O
View Scheme
参考文献
Itoh; Imini; Ogura; et al.
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 4 p. 1375 - 1379
