叔丁基二甲硅基三氟甲磺酸酯合成路线 （共 109 条）
反应条件
in dichloromethane
T=-20°C; 4 h;
参考文献
Alvisi, Chiara; Casolari, Sonia; Costa, Anna Luisa; Ritiani, Monica; Tagliavini, Emilio
Journal of Organic Chemistry, 1998 , vol. 63, # 4 p. 1330 - 1333
反应条件
dimethylsulfide; triethylamine
1.) CH2Cl2, -50 deg C, 30 min 2.) -50 deg C, 1h; Yield given. Multistep reaction;
参考文献
Kim; Kee
Tetrahedron Letters, 1990 , vol. 31, # 20 p. 2899 - 2900
参考文献
Itoh, Takashi; Miyazaki, Michiko; Nagata, Kazuhiro; Ohsawa, Akio
Heterocycles, 1998 , vol. 49, # 1 p. 67 - 71
反应条件
triethylamine in dichloromethane
T=0°C; 1.5 h;
参考文献
Ishikawa, Teruhiko; Aikawa, Toshiaki; Mori, Yumiko; Saito, Seiki
Organic Letters, 2003 , vol. 5, # 1 p. 51 - 54
反应条件
dimethylsulfide; triethylamine
1.) CH2Cl2, -50 deg C, 30 min 2.) -50 deg C, 1h; Yield given. Multistep reaction;
参考文献
Kim; Kee
Tetrahedron Letters, 1990 , vol. 31, # 20 p. 2899 - 2900
反应条件
1: 2-hydroxymethyl-phenol With pyridine; acetic anhydride
T=0°C;
2: t-butyldimethylsiyl triflate in dichloromethane
3: With methanol; potassium carbonate
参考文献
University of Arkansas
Patent: US6657052 B1, 2003 ;
Location in patent: Sheet 37 ;
反应条件
pyridine in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/6926 A1, 2004 ;
Location in patent: Page/Page column 56 ;
WO 2004/006926 A1
反应条件
2,6-dimethylpyridine in dichloromethane
T=20°C; 18 h;
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: WO2006/49889 A1, 2006 ;
Location in patent: Page/Page column 21-22 ;
反应条件
dimethylsulfide; triethylamine
1.) CH2Cl2, -50 deg C, 30 min 2.) -50 deg C, 1h; Yield given. Multistep reaction;
参考文献
Kim; Kee
Tetrahedron Letters, 1990 , vol. 31, # 20 p. 2899 - 2900
反应条件
pyridine in dichloromethane
Cooling with ice;
参考文献
Hamilton, Niall M.; Dawson, Martin; Fairweather, Emma E.; Hamilton, Nicola S.; Hitchin, James R.; James, Dominic I.; Jones, Stuart D.; Jordan, Allan M.; Lyons, Amanda J.; Small, Helen F.; Thomson, Graeme J.; Waddell, Ian D.; Ogilvie, Donald J.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 9 p. 4431 - 4445
