叔丁基二甲硅基三氟甲磺酸酯合成路线 （共 109 条）
反应条件
triethylamine in dichloromethane
T=0 - 20°C; 12 h; Molecular sieveInert atmosphere;
参考文献
Robertson, Keith; Murphy, Cormac D.; Paradisi, Francesca
Amino Acids, 2013 , vol. 45, # 5 p. 1157 - 1168
反应条件
1: 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl With lithium in tetrahydrofuran
Glovebox;
2: t-butyldimethylsiyl triflate in tetrahydrofuran
Glovebox;
参考文献
Gallop, Chris W.D.; Bobin, Mariusz; Hourani, Petra; Dwyer, Jessica; Roe, S. Mark; Viseux, Eddy M. E.
Journal of Organic Chemistry, 2013 , vol. 78, # 13 p. 6522 - 6528
参考文献
Zeneca Limited
Patent: US5486529 A1, 1996 ;
反应条件
1: ethyldiisopropylamine / diethyl ether / 4 h / Ambient temperature
2: benzene / 3 h / Heating
View Scheme
参考文献
Brueckmann, Ralf; Maas, Gerhard
Chemische Berichte, 1987 , vol. 120, p. 635 - 642
反应条件
triethylamine in dichloromethane
0.0833333 h;
参考文献
Mander, Lewis N.; Sethi, S. Paul
Tetrahedron Letters, 1984 , vol. 25, # 51 p. 5953 - 5956
反应条件
triethylamine in dichloromethane
T=0°C; 1.5 h; Title compound not separated from byproducts.;
参考文献
Ishikawa, Teruhiko; Aikawa, Toshiaki; Mori, Yumiko; Saito, Seiki
Organic Letters, 2003 , vol. 5, # 1 p. 51 - 54
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 - 0 °C
1.2: tetrahydrofuran; hexane / 4 h / -78 - 25 °C
2.1: n-BuLi / tetrahydrofuran; hexane / 2 h / -78 - -45 °C / quenched at -78 degC
3.1: 91 percent
View Scheme
参考文献
Sakaguchi; Fujita; Suzuki; Higashino; Ohfune
Tetrahedron Letters, 2000 , vol. 41, # 34 p. 6589 - 6592
参考文献
Beifuss, Uwe; Gehm, Henning; Noltemeyer, Mathias; Schmidt, Hans-Georg
Angewandte Chemie, 1995 , vol. 107, # 6 p. 705 - 707
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
T=20°C; 0.5 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; WU, Yong-Jin
Patent: WO2012/162334 A1, 2012 ;
Location in patent: Page/Page column 23 ;
参考文献
Liu, Chunjian; Bao, Guanglin; Burnell, D. Jean
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 20 p. 2644 - 2656
