叔丁基二甲硅基三氟甲磺酸酯合成路线 （共 109 条）
反应条件
in dichloromethane
T=0°C; 0.5 h;
参考文献
LG LIFE SCIENCES, LTD.
Patent: WO2009/38411 A2, 2009 ;
Location in patent: Page/Page column 39 ;
WO 2009/038411 A2
反应条件
1: 2,6-lutidine
2: O3, dimethyl sulfide
View Scheme
参考文献
Keenan, Richard M.; Eppley, Daniel F.; Tomaszek, Thaddeus A.
Tetrahedron Letters, 1995 , vol. 36, # 6 p. 819 - 822
反应条件
2,6-dimethylpyridine in dichloromethane
T=0°C; 1 h; Inert atmosphere;
参考文献
Marcela Castano; Cardona, Wilson; Quinones, Winston; Robledo, Sara; Echeverri, Fernando
Molecules, 2009 , vol. 14, # 7 p. 2491 - 2500
反应条件
dimethylsulfide; triethylamine
1.) CH2Cl2, -50 deg C, 30 min 2.) -50 deg C, 1h; Yield given. Multistep reaction;
参考文献
Kim; Kee
Tetrahedron Letters, 1990 , vol. 31, # 20 p. 2899 - 2900
反应条件
1: 1.) 1.5 M t-butyllithium / 1.) ether, pentane, -70 deg C, 106 min; 2.) THF, -70 deg C, 4 min; 0 deg C, 20 min
2: 60 percent / sodium carbonate, 1.2 M hydrogen chloride / 0.08 h
View Scheme
参考文献
Duhamel, L.; Gralak, J.; Ngono, B.
Journal of Organometallic Chemistry, 1989 , vol. 363, p. C4 - C6
反应条件
1: CH2Cl2
2: tetrahydrofuran / 3 h / Ambient temperature; impurity (0.4percent) 2-butyl isomer
View Scheme
参考文献
Akiba, Kin-ya; Iseki, Yuji; Wada, Makoto
Tetrahedron Letters, 1982 , vol. 23, # 38 p. 3935 - 3936
反应条件
triethylamine in dichloromethane
参考文献
Spino, Claude; Liu, Gang; Tu, Noah; Girard, Suzanne
Journal of Organic Chemistry, 1994 , vol. 59, # 19 p. 5596 - 5608
反应条件
1: 89 percent / Et3N / CH2Cl2 / 4 h / Ambient temperature
2: 81 percent / Ag(CF3COO), (2Z,6E)-3-<<(tert-butyl)dimethylsiloxy>methyl>-7-methyl-9-(2',6',6'-trimethylcyclohex-1'-enyl)nona-2,6-dien-1-ol / CH2Cl2
View Scheme
参考文献
Jefford; Rossier; Boukouvalas; Huang
Helvetica Chimica Acta, 1994 , vol. 77, # 3 p. 661 - 667
反应条件
pyridine in dichloromethane
T=20°C; 16 h;
参考文献
ARDEA BIOSCIENCES, INC.
Patent: WO2008/89459 A1, 2008 ;
Location in patent: Page/Page column 47 ;
反应条件
2,6-dimethylpyridine
1.) dichloromethane, room t., 2 h; 2.) 0 degC, 2 h; Yield given. Multistep reaction;
参考文献
Franck, Xavier; Figadere, Bruno; Cave, Andre
Tetrahedron Letters, 1995 , vol. 36, # 5 p. 711 - 714
