1-乙酰基-2,3,5-三苯甲酰氧基-1-beta-D-呋喃核糖合成路线 （共 164 条）
反应条件
trimethylsilylazide; tin(IV) chloride in dichloromethane
12 h; Ambient temperature;
参考文献
Stimac, Anton; Kobe, Joze
Carbohydrate Research, 1992 , vol. 232, # 2 p. 359 - 365
反应条件
aluminium trichloride in dichloromethane
T=0°C; 0.166667 h;
参考文献
Logue, Marshall W.; Han, Byung Hee
Carbohydrate Research, 1983 , vol. 121, p. 287 - 298
反应条件
trimethylsilylazide in dichloromethane
T=20°C; Rearrangement; azidation; deacetylation; 3 h; Further byproducts given;
参考文献
Stimac, Anton; Kobe, Joze
Carbohydrate Research, 2000 , vol. 324, # 3 p. 149 - 160
反应条件
trimethylsilyl trifluoromethanesulfonate; trimethylsilylazide in dichloromethane
216 h; Ambient temperatureother catalysts;
参考文献
Stimac, Anton; Kobe, Joze
Carbohydrate Research, 1992 , vol. 232, # 2 p. 359 - 365
反应条件
methanol; ammonium sulfate; ammonia; tin(IV) chloride; 1,1,1,3,3,3-hexamethyl-disilazane
Yield given. Multistep reaction;
参考文献
Patil, Vemanna D.; Wise, Dean S.; Townsend, Leroy B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1853 - 1858
反应条件
methanol; ammonia; tin(IV) chloride; N,N-bis(trimethylsilyl)acetamide
Yield given. Multistep reaction;
参考文献
Patil, Vemanna D.; Wise, Dean S.; Townsend, Leroy B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1853 - 1858
反应条件
1: 48 percent / stannic chloride / 1,2-dichloro-ethane / 3 h / Ambient temperature
2: 1.) BCl3; 2.) CH3OH / 1.) CH2Cl2, -78 deg C, 2 h; 2.) -78 deg C, 2 h, room temp. 30 min.
3: 60 percent / phosphorus pentasulfide / pyridine; H2O / 12 h / Heating
4: 1.) 1N NaOH; 2.) 1N NaOH / 1.) aq. ethanol, room temp., 2 h; 2.) room temp., 1 h.
5: 30 percent / NH3 (l) / 4 h / 150 °C / steel bomb
View Scheme
参考文献
Gagnier; Halat; Otter
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 2 p. 481 - 489
反应条件
tin(IV) chloride in hexane; dichloromethane; ethyl acetate; 1,2-dichloro-ethane
参考文献
Hoffmann-La Roche Inc.
Patent: US4115641 A1, 1978 ;
反应条件
chloro-trimethyl-silane; trifluorormethanesulfonic acid; 1,1,1,3,3,3-hexamethyl-disilazane in acetonitrile
Vorbruggen ribosylation; 1 h;
参考文献
Zhang, Ning; Chen, Huan-Ming; Sood, Ramesh; Kalicharran, Kishna; Fattom, Ali I; Naso, Robert B; Barnard, Dale L; Sidwell, Robert W; Hosmane, Ramachandra S
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 23 p. 3391 - 3394
反应条件
1: N,O-bis(trimethylsilyl)acetamide; trimethylsilyl triflate / acetonitrile / 0.08 h / 130 °C / microwave irradiation
2: NH3 / methanol / 16 h / 50 °C
View Scheme
参考文献
Bookser, Brett C.; Raffaele, Nicholas B.
Journal of Organic Chemistry, 2007 , vol. 72, # 1 p. 173 - 179
