Alpha-(二正丁胺甲基)-2,7-二氯芴-4-甲醇合成路线 （共 5 条）
反应条件
sodium tetrahydroborate in ethanol T=140°C; 3 h;
参考文献
Beutler, Ulrich; Fuenfschilling, Peter C.; Steinkemper, Andreas
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 341 - 345
参考文献
Journal of Medicinal Chemistry, , vol. 17, # 9 p. 1009 - 1012
反应条件
1: AlCl3, aluminium chloride / dichloromethane / -5 - 0 °C 2: sodium tetrahydroborate / ethanol / 1 h / -5 - 5 °C 3: sodium tetrahydroborate / ethanol / 3 h / 140 °C View Scheme
参考文献
Organic Process Research and Development, , vol. 11, # 3 p. 341 - 345
反应条件
1: chlorine / acetic acid / 15 h / 35 - 45 °C 2: AlCl3, aluminium chloride / dichloromethane / -5 - 0 °C 3: sodium tetrahydroborate / ethanol / 1 h / -5 - 5 °C 4: sodium tetrahydroborate / ethanol / 3 h / 140 °C View Scheme
参考文献
Organic Process Research and Development, , vol. 11, # 3 p. 341 - 345
反应条件
oxygen; sodium hydroxide in ethanol
T=23 - 70°C; 6 h;
参考文献
Beutler, Ulrich; Fuenfschilling, Peter C.; Steinkemper, Andreas
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 341 - 345
