2-甲基-4-氨基嘧啶-5-腈合成路线 （共 53 条）
反应条件
nickel T=150°C; Hydrogenation;
参考文献
Sekiya
Yakugaku Zasshi, 1950 , vol. 70, p. 520,522,523
Chem.Abstr., 1951 , p. 5640
反应条件
1: palladium cathode / elektrochemische Reduktion View Scheme
参考文献
Matsukawa
Yakugaku Zasshi, 1942 , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., 1951 , p. 4724
反应条件
1: aq. NaOH solution View Scheme
参考文献
Matsukawa et al.
Yakugaku Zasshi, 1950 , vol. 70, p. 283,284
Chem.Abstr., 1951 , p. 2894
反应条件
hydrogenchloride; palladium; acetic acid Hydrogenation;
参考文献
Baxter, Robert L.; Hanley, A. Bryan; Chan, Henry W. S.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 11 p. 2963 - 2966
反应条件
1: With sulfuric acid; hydrogen; palladium 10 on activated carbon in water T=20°C; P=1551.49 - 2585.81 Torr; 1.25 h; 2: With ammonium hydroxide in water
参考文献
Anderson, Kevin; Chen, Yi; Chen, Zhi; Luk, Kin-Chun; Rossman, Pamela Loreen; Sun, Hongmao; Wovkulich, Peter Michael
Patent: US2012/184542 A1, 2012 ;
Location in patent: Page/Page column 58; 59 ;
US 20120184542 A1
反应条件
hydrogenchloride; formic acid; nickel monoaluminide in water; hydrogen
参考文献
Warner-Lambert Company
Patent: US4271164 A1, 1981 ;
反应条件
nickel T=80 - 100°C; 0.75 h;
参考文献
Baxter, Robert L.; Hanley, A. Bryan; Chan, Henry W. S.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 11 p. 2963 - 2966
反应条件
ammonia; hydrogen in methanol T=100°C; P=30003 Torr; 5 h; AutoclaveSaturated solutionLarge scale reaction;
参考文献
Zhao, Lei; Ma, Xiao-Dong; Chen, Fen-Er
Organic Process Research and Development, 2012 , vol. 16, # 1 p. 57 - 60
反应条件
1: palladium cathode / elektrochemische Reduktion 3: toluene; P2S5 View Scheme
参考文献
Matsukawa
Yakugaku Zasshi, 1942 , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., 1951 , p. 4724
反应条件
1: aqueous H2O2 2: acetic acid anhydride View Scheme
参考文献
Chatterjee; Anand
Journal of Scientific and Industrial Research, 1958 , vol. 17 B, p. 63,68
