4-甲氧基苯甲酸-α-13C合成路线 （共 7 条）
反应条件
potassium carbonate in acetone 24 h; Heating;
参考文献
Cho; Beale; Graff; Mocek; Nakagawa; Omura; Floss
Journal of the American Chemical Society, 1993 , vol. 115, # 26 p. 12296 - 12304
反应条件
1: 97 percent / BH3*THF / 1 h / 0 °C 2: 84 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Cho; Beale; Graff; Mocek; Nakagawa; Omura; Floss
Journal of the American Chemical Society, 1993 , vol. 115, # 26 p. 12296 - 12304
反应条件
borane-THF T=0°C; 1 h;
参考文献
Gable, Kevin P.; Zhuravlev, Fedor A.
Journal of the American Chemical Society, 2002 , vol. 124, # 15 p. 3970 - 3979
反应条件
1: para-iodoanisole With tert.-butyl lithium in diethyl ether; pentane
T=-78°C; 1.5 h;
2: 13CO2 in diethyl ether; pentane
T=-40 - 20°C; Further stages.;
参考文献
Gable, Kevin P.; Zhuravlev, Fedor A.
Journal of the American Chemical Society, 2002 , vol. 124, # 15 p. 3970 - 3979
反应条件
magnesium
1) ether, 2) ether, 0 deg C, 70 min; Yield given. Multistep reaction;
参考文献
Takeuchi, Ken'ichi; Murai, Osamu; Matsui, Shin; Inoue, Takeshi; Kitagawa, Toshikazu; Okamoto, Kunio
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 9 p. 1301 - 1310
反应条件
in chloroform-d1; 1,2-dichloro-ethane
T=75°C; 0.0416667 h; Mechanism;
参考文献
Kitagawa; Nishimura Takeuchi; Okamoto
Tetrahedron Letters, 1991 , vol. 32, # 27 p. 3187 - 3190
反应条件
in 1,2-dichloro-ethane
T=75°C; 51 h; Product distributionMechanism;
参考文献
Takeuchi, Ken'ichi; Murai, Osamu; Matsui, Shin; Inoue, Takeshi; Kitagawa, Toshikazu; Okamoto, Kunio
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 9 p. 1301 - 1310
