(4-甲氧基苯基)-1-吡咯烷甲酮合成路线 (共 17 条)
反应条件
CrO3-3.5-dimethylpyrazole in dichloromethane 24 h; Ambient temperature;
参考文献
Blay, Gonzalo; Cardona, Luz; Garcia, Begona; Garcia, Cristina L.; Pedro, Jose R.
Tetrahedron Letters, 1997 , vol. 38, # 47 p. 8257 - 8260
反应条件
4-(N,N-dimethlyamino)pyridine; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane
T=90°C; 0.333333 h; Sealed tubeMicrowave irradiation;
参考文献
Baburajan, Poongavanam; Elango, Kuppanagounder P.
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 1006 - 1010
反应条件
in dichloromethane
T=20°C; 2 h;
参考文献
Wu, Xianglong; Fan, Wutu; Pan, Yalei; Zhai, Yuankun; Niu, Yinbo; Li, Chenrui; Mei, Qibing
Molecules, 2014 , vol. 19, # 1 p. 1034 - 1046
反应条件
triethylamine in tetrahydrofuran
Acylation; 1 h; Heating;
参考文献
Sasse; Sadek; Ligneau; Elz; Pertz; Luger; Ganellin; Arrang; Schwartz; Schunack; Stark
Journal of Medicinal Chemistry, 2000 , vol. 43, # 17 p. 3335 - 3343
反应条件
tert.-butylhydroperoxide in acetonitrile
T=80°C; 5 h;
参考文献
Ekoue-Kovi, Kekeli; Wolf, Christian
Organic Letters, 2007 , vol. 9, # 17 p. 3429 - 3432
反应条件
4-(N,N-dimethlyamino)pyridine in acetonitrile
T=70°C; 48 h; Inert atmosphere;
参考文献
Bai, Jianfei; Zambron, Bartosz K.; Vogel, Pierre
Organic Letters, 2014 , vol. 16, # 2 p. 604 - 607
反应条件
potassium carbonate
T=130°C; P=9308.91 Torr; 5 h; AutoclaveInert atmosphereIonic liquid;
参考文献
Zhu, Yinghuai; Chuanzhao, Li; Biying, Algin Oh; Sudarmadji, Meriska; Chen, Anqi; Tuan, Dang Thanh; Seayad, Abdul M
Dalton Transactions, 2011 , vol. 40, # 36 p. 9320 - 9325
反应条件
4-(N,N-dimethlyamino)pyridine; tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine in 1,4-dioxane
T=65°C; 15 h;
参考文献
Nordeman, Patrik; Odell, Luke R.; Larhed, Mats
Journal of Organic Chemistry, 2012 , vol. 77, # 24 p. 11393 - 11398
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
T=111°C; 2 h;
参考文献
Lindsay, Charles M.; Widdowson, David A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 569 - 574
反应条件
triphenylphosphine; palladium dichloride in water
T=20°C; Sonogashira coupling; 12 h;
参考文献
Liang, Bo; Huang, Mengwei; You, Zejin; Xiong, Zhengchang; Lu, Kui; Fathi, Reza; Chen, Jiahua; Yang, Zhen
Journal of Organic Chemistry, 2005 , vol. 70, # 15 p. 6097 - 6100