3-(3-氟-4-羟基苯基)丙酸合成路线 （共 3 条）
反应条件
pyridine hydrochloride
T=190°C; 1.5 h;
参考文献
Shoda, Motoshi; Kuriyama, Hiroshi
Patent: US2004/44258 A1, 2004 ;
Location in patent: Page 60 ;
反应条件
water; lithium hydroxide hydrate in tetrahydrofuran; methanol
参考文献
Shen, Zhongqi; Siva Ramamoorthy; Hatzenbuhler, Nicole T.; Evrard, Deborah A.; Childers, Wayne; Harrison, Boyd L.; Chlenov, Michael; Hornby, Geoffrey; Smith, Deborah L.; Sullivan, Kelly M.; Schechter, Lee E.; Andree, Terrance H.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 222 - 227
反应条件
sodium chloride; AlCl3, aluminium chloride
T=185°C; 0.25 h;
参考文献
WYETH
Patent: WO2006/138549 A1, 2006 ;
Location in patent: Page/Page column 78-79 ;
WO 2006/138549 A1
