2-(4-甲基苯基)乙醇合成路线 （共 73 条）
反应条件
1: benzene; PBr3 / 0 °C 2: ethanol View Scheme
参考文献
Speer; Hill
Journal of Organic Chemistry, 1937 , vol. 2, p. 139,143
反应条件
in water; acetic acid 0.833333 h; Heating / reflux;
参考文献
CHATTOPADHYAYA, Jyoti
Patent: WO2007/64291 A1, 2007 ;
Location in patent: Page/Page column 17 ;
反应条件
molecular sieve; pyridinium chlorochromate in dichloromethane T=20°C; 8 h;
参考文献
Tetrahedron Letters, , vol. 44, # 6 p. 1275 - 1278
反应条件
1H-imidazole in toluene
T=85°C; 1.5 h; Inert atmosphere;
参考文献
Ellwood, Adam R.; Porter, Michael J.
Journal of Organic Chemistry, 2009 , vol. 74, # 20 p. 7982 - 7985
反应条件
1H-imidazole; iodine; triphenylphosphine in dichloromethane
参考文献
Lanni Jr., Thomas B.; Greene, Keri L.; Kolz, Christine N.; Para, Kimberly S.; Visnick, Melean; Mobley, James L.; Dudley, David T.; Baginski, Theodore J.; Liimatta, Marya B.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 756 - 760
反应条件
1H-imidazole; methyl iodide in tetrahydrofuran
4 h; Inert atmosphereReflux;
参考文献
Ellwood, Adam R.; Porter, Michael J.
Journal of Organic Chemistry, 2009 , vol. 74, # 20 p. 7982 - 7985
反应条件
1: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; sodium periodate; sodium bromide / dichloromethane; water / 24 h / 20 °C / |Schlenk technique; |Inert atmosphere
2: zinc(II) chloride / ethanol / 1 h / 100 °C / |Inert atmosphere; |Schlenk technique
View Scheme
参考文献
Nagase, Yuta; Shirai, Hiroyuki; Kaneko, Masayoshi; Shirakawa, Eiji; Tsuchimoto, Teruhisa
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 9 p. 1456 - 1459
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; potassium tert-butylate in para-xylene
T=120°C; 4 h; Inert atmosphere;
参考文献
Obora, Yasushi; Anno, Yuka; Okamoto, Ryuhei; Matsu-Ura, Toyomi; Ishii, Yasutaka
Angewandte Chemie - International Edition, 2011 , vol. 50, # 37 p. 8618 - 8622
反应条件
1: PBr3 / benzene
2: Na / ethanol
3: (i) H2SO4, (ii) KOH, EtOH
4: diethyl ether
5: (i) Na, MeOH, (ii) /BRN= 969135/
6: aq. HCl / acetic acid
7: (i) Et2O, benzene, (ii) Pd-C
View Scheme
参考文献
Chatterjee,D.N.; Chakravorty,S.R.
Journal of the Indian Chemical Society, 1976 , vol. 53, p. 610 - 616
反应条件
1: PBr3 / benzene
2: Na / ethanol
View Scheme
参考文献
Chatterjee,D.N.; Chakravorty,S.R.
Journal of the Indian Chemical Society, 1976 , vol. 53, p. 610 - 616
