2-(4-甲基苯基)乙醇合成路线 (共 73 条)
反应条件
1: PBr3 / benzene
2: Na / ethanol
3: (i) H2SO4, (ii) KOH, EtOH
4: diethyl ether
5: (i) Na, MeOH, (ii) /BRN= 969135/
6: aq. HCl / acetic acid
View Scheme
参考文献
Chatterjee,D.N.; Chakravorty,S.R.
Journal of the Indian Chemical Society, 1976 , vol. 53, p. 610 - 616
反应条件
1: fuming hydrogen bromide
2: 1.) Mg, iodine / 1.) diethyl ether, reflux, 1 h, 2.) room temperature, 1 h, reflux, 1 h
View Scheme
参考文献
Ellis-Davies, Graham C. R.; Gilbert, Andrew; Heath, Peter; Lane, Jon C.; Warrington, John V.; Westover, David L.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , p. 1833 - 1842
反应条件
1: NaHSO4 / Entfernen des entstehenden Wassers
2: nickel /kieselguhr / 140 °C / 25742.8 Torr / Hydrogenation
3: HBr / allmaehliches Erhitzen auf Siedetemperatur
View Scheme
参考文献
Dow Chem. Co.
Patent: US2355586 , 1940 ;