3-苯基-3-羟基-1-氧杂环丁烷合成路线 (共 3 条)
反应条件
1: bromobenzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.166667 h;
2: oxetan-3-one in tetrahydrofuran; hexane
T=-78°C; 0.166667 h;
参考文献
Wang, Zhaobin; Chen, Zhilong; Sun, Jianwei
Angewandte Chemie - International Edition, 2013 , vol. 52, # 26 p. 6685 - 6688
Angew. Chem., 2013 , vol. 125, # 26 p. 6817 - 6820,4
反应条件
potassium tert-butylate
1) 5 min, 2) CDCl3, 12 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Friedrich, Louis E.; Lam, Patrick Yuk-Sun
Journal of Organic Chemistry, 1981 , vol. 46, # 2 p. 306 - 311
反应条件
in methanol
T=25°C; Irradiation;
参考文献
Mayo, Paul de; Ramnath, N.
Canadian Journal of Chemistry, 1986 , vol. 64, p. 1293 - 1296