3-(2-二甲基氨基乙基)-5-硝基吲哚合成路线 （共 6 条）
反应条件
dimethyl amine in ethanol
参考文献
Bristol-Myers Squibb Company
Patent: US5382592 A1, 1995 ;
US 5382592 A
参考文献
Shaw; Woolley
Journal of the American Chemical Society, 1953 , vol. 75, p. 1877,1880
反应条件
1: phthalimide / diethyl ether / 72 h / Ambient temperature
2: diethyl ether / 1 h / Ambient temperature
3: 1.) borane, 2.) CsF, sodium carbonate / 1.) THF, RT, 16 h, 2.) EtOH, reflux, 16 h
View Scheme
参考文献
Macor; Post; Ryan
Synthetic Communications, 1993 , vol. 23, # 1 p. 65 - 72
反应条件
1: diethyl ether / 1 h / Ambient temperature
2: 1.) borane, 2.) CsF, sodium carbonate / 1.) THF, RT, 16 h, 2.) EtOH, reflux, 16 h
View Scheme
参考文献
Macor; Post; Ryan
Synthetic Communications, 1993 , vol. 23, # 1 p. 65 - 72
反应条件
borane; sodium carbonate; cesium fluoride
1.) THF, RT, 16 h, 2.) EtOH, reflux, 16 h; Yield given. Multistep reaction;
参考文献
Macor; Post; Ryan
Synthetic Communications, 1993 , vol. 23, # 1 p. 65 - 72
反应条件
hydrogen; palladium on activated charcoal in ethanol
P=2280 Torr; 6 h;
参考文献
Macor; Post; Ryan
Synthetic Communications, 1993 , vol. 23, # 1 p. 65 - 72
