Beta-咔啉-3-羧酸甲酯合成路线 （共 40 条）
反应条件
1: 91 percent / aq. base 2: 61 percent / H2SO4 / 8 h / Heating View Scheme
参考文献
Mehta, Pratibha; Saxena, Anil K.; Gulati, A.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 140 - 143
反应条件
1: 65 percent / Pb(OAc)4 / acetic acid / 1 h 2: 96 percent / NaOH / ethanol; H2O / 0.5 h / Heating 3: 75 percent / 1,1'-carbonyldiimidazole / dimethylformamide / Ambient temperature View Scheme
参考文献
Lippke; Muller; Schunack
Journal of Pharmaceutical Sciences, 1985 , vol. 74, # 6 p. 676 - 680
反应条件
sulfur in 1,4-dioxane; xylene
144 h; Heating;
参考文献
Cain; Weber; Guzman; Cook; Barker; Rice; Crawley; Paul; Skolnick
Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1081 - 1091
反应条件
trichloroisocyanuric acid; triethylamine in N,N-dimethyl-formamide
T=-20 - 0°C; 2 h; Inert atmosphere;
参考文献
Ikeda, Reiko; Kimura, Takanori; Tsutsumi, Tatsuya; Tamura, Syunsuke; Sakai, Norio; Konakahara, Takeo
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 10 p. 3506 - 3515
反应条件
1: SOCl2
2: S / xylene; dioxane
View Scheme
参考文献
Yu, Xiaolin; Lin, Wei; Li, Jingyun; Yang, Ming
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 12 p. 3127 - 3130
反应条件
selenium(IV) oxide in 1,4-dioxane
4 h; Heating;
参考文献
Gatta; Misiti
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 4 p. 1183 - 1187
反应条件
acetic acid; triethylamine in methanol
1 h; Heating;
参考文献
Previero, A.; Barry, L-G.; Torreilles, J.; Fleury, B.; Letellier, S.; Maupas, B.
Tetrahedron, 1984 , vol. 40, # 1 p. 221 - 234
反应条件
n-ethyl morpholine; acetic acid in methanol
T=23°C; 1.33333 h;
参考文献
Previero, A.; Barry, L-G.; Torreilles, J.; Fleury, B.; Letellier, S.; Maupas, B.
Tetrahedron, 1984 , vol. 40, # 1 p. 221 - 234
反应条件
lead(IV) acetate in acetic acid
参考文献
Maclaren, John A.
Australian Journal of Chemistry, 1989 , vol. 42, # 6 p. 813 - 821
反应条件
trichlorophosphate
T=28°C; Bischler-Napieralski reaction; 0.5 h;
参考文献
Pal, Bikash; Jaisankar, Parasuraman; Sesha Giri, Venkatachalam; Mondal, Swastik; Mukherjee, Monika
Tetrahedron Letters, 2004 , vol. 45, # 34 p. 6489 - 6492
