Beta-咔啉-3-羧酸甲酯合成路线 （共 40 条）
参考文献
Tada; Saeki; Oikawa
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 5 p. 1450 - 1454
反应条件
1: H(+)
2: SOCl2
3: S / xylene; dioxane
View Scheme
参考文献
Yu, Xiaolin; Lin, Wei; Li, Jingyun; Yang, Ming
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 12 p. 3127 - 3130
反应条件
selenium(IV) oxide in 1,4-dioxane
4 h; Heating;
参考文献
Gatta; Misiti
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 4 p. 1183 - 1187
反应条件
silica gel; trichlorophosphate
Bischler-Napieralski condensation; 0.15 h; microwave irradiation;
参考文献
Pal, Bikash; Jaisankar, Parasuraman; Giri, Venkatachalam S.
Synthetic Communications, 2003 , vol. 33, # 13 p. 2339 - 2348
反应条件
1: 85 percent / thionyl chloride / Ambient temperature
2: 83 percent / triethylamine, acetic acid / methanol / 1 h / Heating
View Scheme
参考文献
Previero, A.; Barry, L-G.; Torreilles, J.; Fleury, B.; Letellier, S.; Maupas, B.
Tetrahedron, 1984 , vol. 40, # 1 p. 221 - 234
反应条件
1: 30 percent / SeO2 / dioxane / 4 h / Heating
2: 85 percent / SeO2 / dioxane / 4 h / Heating
View Scheme
参考文献
Gatta; Misiti
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 4 p. 1183 - 1187
反应条件
1.1: sodium hydroxide / water / 5 h / 20 °C / Reflux
1.2: pH 5
2.1: thionyl chloride / 24 h / -10 °C / Reflux
2.2: pH 8
3.1: trichloroisocyanuric acid; triethylamine / N,N-dimethyl-formamide / 2 h / -20 - 0 °C
View Scheme
参考文献
Ikeda, Reiko; Iwaki, Toshie; Iida, Tomoko; Okabayashi, Takasumi; Nishi, Eishiro; Kurosawa, Masaki; Sakai, Norio; Konakahara, Takeo
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 2 p. 636 - 646
反应条件
acetic acid; triethylamine in methanol
1 h; Heating;
参考文献
Maclaren, John A.
Australian Journal of Chemistry, 1989 , vol. 42, # 6 p. 813 - 821
反应条件
1: triethylamine / CHCl3 / 1.) RT, 16 h, 2.) reflux, 6 h
2: 4-toluenesulfonic acid / acetonitrile / 48 h / Ambient temperature
3: triethylamine, acetic acid / methanol
View Scheme
参考文献
Maclaren, John A.
Australian Journal of Chemistry, 1989 , vol. 42, # 6 p. 813 - 821
反应条件
1: 4-toluenesulfonic acid / acetonitrile / 48 h / Ambient temperature
2: triethylamine, acetic acid / methanol
View Scheme
参考文献
Maclaren, John A.
Australian Journal of Chemistry, 1989 , vol. 42, # 6 p. 813 - 821
