N-(4-氯苄基)-2-丙烯-1-胺合成路线 （共 5 条）
反应条件
1: in methanol
2 h; Cooling with ice;
2: With sodium tetrahydroborate in methanol
2.08333 h;
参考文献
Buhrlage, Sara; Dockendorff, Chris; Foley, Mike; Kim, Han-Je; Germain, Andrew; MacPherson, Lawrence; Nag, Partha; Schreiber, Stuart; Ting, Amal; Weiwer, Michel; Youngsaye, Willmen
Patent: US2014/94462 A1, 2014 ;
Location in patent: Paragraph 0966 ;
反应条件
methanol; magnesium
T=-23°C; 2 h;
参考文献
Pak, Chwang Siek; Kim, Tae Hoon; Ha, Sung Jin
Journal of Organic Chemistry, 1998 , vol. 63, # 26 p. 10006 - 10010
反应条件
1: phenyllithium With copper(l) iodide in diethyl ether
cooling;
2: 2-(bromomethyl)-1-lt;(4-chlorophenyl)methylgt;aziridine in diethyl ether
T=-78 - 20°C; 20 h;
参考文献
D'Hooghe, Matthias; Rottiers, Mario; Jolie, Robrecht; De Kimpe, Norbert
Synlett, 2005 , # 6 art. no. G45704ST, p. 931 - 934
反应条件
1: MgSO4 / CH2Cl2
2: Br2 / CH2Cl2
3: NaBH4 / methanol / Heating
4: 78 percent / [CH2=CH(Me)]2CuLi / diethyl ether / 6 h / -78 - 20 °C
View Scheme
参考文献
D'Hooghe, Matthias; Rottiers, Mario; Jolie, Robrecht; De Kimpe, Norbert
Synlett, 2005 , # 6 art. no. G45704ST, p. 931 - 934
反应条件
1: 97 percent / NaBH4 / methanol / 2 h / Heating
2: 50 percent / Zn(Cu) / H2O; methanol / 6 h / Irradiation
View Scheme
参考文献
Kimpe, Norbert De; Jolie, Rob; Smaele, Dirk De
Journal of the Chemical Society, Chemical Communications, 1994 , # 10 p. 1221 - 1222
