1-(2-氨基-3,5-二甲基苯基)-乙酮合成路线 (共 4 条)
反应条件
BCl3 in diethyl ether; dichloromethane; ethyl acetate; 1,2-dichloro-ethane; acetonitrile
参考文献
Texas Biotechnology Corporation
Patent: US6432994 B1, 2002 ;
US 6432994 B1
反应条件
in diethyl ether; dichloromethane; ethyl acetate; 1,2-dichloro-ethane; acetonitrile
参考文献
Wu, Chengde; Blok, Natalie; Kogan, Timothy; Keller, Karin; Woodard, Patricia
Patent: US2002/91270 A1, 2002 ;
反应条件
hydrogenchloride; tin
Heating;
参考文献
Doppler,T. et al.
Helvetica Chimica Acta, 1979 , vol. 62, p. 271 - 303
反应条件
1: 85 percent / BH3*THF / 20 °C
2: 80 percent / Et3SiH; TFA / Heating
View Scheme
参考文献
Wu; Decker; Blok; Li; Bourgoyne; Bui; Keller; Knowles; Stavros; Holland; Brock; Dixon
Journal of Medicinal Chemistry, 2001 , vol. 44, # 8 p. 1211 - 1216